ELANE, elastase, neutrophil expressed, 1991

N. diseases: 346; N. variants: 33
Disease: Coronary Artery Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.030 Biomarker disease BEFREE These findings suggest that 4-HNE may be an important marker of depressive symptoms in CAD and may be involved in its progression. 30267986 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.030 Biomarker disease BEFREE This study investigated whether greater pre-treatment oxidative stress, measured by the ratios of late-stage lipid peroxidation markers (malondialdehyde [MDA], 4-hydroxy-2-nonenal [4-HNE], and 8-isoprostane [8-ISO]) to an early-stage marker (lipid hydroperoxides [LPH]), predicted n-3 PUFA antidepressant benefits in CAD. 27742581 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.030 GeneticVariation disease BEFREE Neutrophil elastase gene variation and coronary heart disease. 17622939 2007