ELAVL2, ELAV like RNA binding protein 2, 1993

N. diseases: 199; N. variants: 9
Disease: Degenerative polyarthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.050 Biomarker disease BEFREE Moreover, protein-protein interaction (PPI) network construction was applied for exploring the hub genes in osteoarthritis. 31139654 2019
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.050 Biomarker disease BEFREE BIRC2 and CSNK1E were respective hub genes of RA- and OA-specific PPI network. 30834598 2019
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.050 AlteredExpression disease BEFREE Microarray analysis determined PTGS1 was the hub gene in the black module, which was overexpressed in OA synovial cells and tissues compared with normal synovial cells. 30548602 2019
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.050 Biomarker disease BEFREE Based on weighted gene co-expression network analysis (WGCNA) and the identification of differentially expressed genes (DEGs), the microarray data were further analyzed to identify hub genes, key transcription factors (TFs) and pivotal signaling pathways involved in the pathogenesis of OA. 31572500 2019
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.050 GeneticVariation disease BEFREE Importantly, IKBKB, NFKBIA, MAPK8, MAPK9, and MAPK10 may be the hub genes affected by icariin when providing its beneficial effects on OA. 30506715 2018