EMX2, empty spiracles homeobox 2, 2018

N. diseases: 59; N. variants: 2
Disease: Tumor Cell Invasion ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.030 AlteredExpression phenotype BEFREE Overexpressing EMX2 in EAC cell lines enhanced the expression of apoptotic markers, inhibited cell migration and invasion, led to the upregulation of E‑cadherin and the downregulation of mesenchymal markers, and suppressed AKT, mTOR and S6K phosphorylation. 31432154 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.030 Biomarker phenotype BEFREE In addition, EMX2 also inhibited the migration and invasion of CRC cells. 27712600 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.030 AlteredExpression phenotype BEFREE Reduced EMX2 expression was correlated with the tumor stage (P = 0.023), grade (P = 0.016), and the depth of myometrial invasion (P = 0.04), but not with age, pathologic subtype, lymph node metastasis, lymph vascular space invasion, or ER/PR/p53 status. 23370654 2013