Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0035204
Disease: Respiration Disorders
Respiration Disorders
0.010 GeneticVariation group BEFREE A high degree of ENT1 inhibition (≥13.3x K<sub>i</sub>, ≥4x IC<sub>50</sub>) associated with increased incidence of bronchospasm/severe dyspnoea for patients with respiratory disease only, whereas a lower degree of ENT1 inhibition (≥0.1x K<sub>i</sub>, ≥0.05x IC<sub>50</sub>) associated with a tolerable level of dyspnoea in both respiratory and cardiovascular disease patients. 28041785 2017