EPHX1, epoxide hydrolase 1, 2052

N. diseases: 196; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.320 GeneticVariation phenotype LHGDN Although we could not find any association between genetic variability in exon 3 and 4 of EPHX and pre-eclampsia, genetic variability in these two exons jointly modifies the predicted enzyme activity and may be a risk factor for pre-eclampsia. 17212663 2007
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.320 GeneticVariation phenotype LHGDN The study also determined whether genetic variability in the gene encoding for microsomal epoxide hydrolase (EPHX) contributes to individual differences in susceptibility to the development of preeclampsia. 12173035 2002
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.320 Biomarker phenotype CTD_human The study also determined whether genetic variability in the gene encoding for microsomal epoxide hydrolase (EPHX) contributes to individual differences in susceptibility to the development of preeclampsia. 12173035 2002
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia
0.320 Biomarker phenotype CTD_human In addition, a significant association was found between predicted EPHX activity and pre-eclampsia. 11283205 2001