AKT2, AKT serine/threonine kinase 2, 208

N. diseases: 264; N. variants: 18
Disease: Renal fibrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151650
Disease: Renal fibrosis
Renal fibrosis 		0.020 AlteredExpression disease BEFREE Overexpression of miR‑21 may be activated by AKT2 and contribute to renal fibrosis by negatively regulating IFNG expression. 28714020 2017
CUI: C0151650
Disease: Renal fibrosis
Renal fibrosis 		0.020 Biomarker disease BEFREE Our findings suggest that Akt2 partially contributes to interstitial fibrosis following UUO and that inhibition of this signaling pathway may provide a novel approach of prevent progression of renal fibrosis. 25148525 2014