AKT2, AKT serine/threonine kinase 2, 208

N. diseases: 264; N. variants: 18
Disease: Solid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.020 Biomarker phenotype BEFREE In mammalian cells, hyperactivation of Akt2 exclusively facilitates the survival of solid tumors by interfering with cell cycle progression. 30354009 2019
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.020 Biomarker phenotype BEFREE Moreover, AKT2 is also exclusively required for the maintenance and survival of other PTEN-deficient solid tumors, including breast cancer and glioblastoma. 24838891 2014