AKT2, AKT serine/threonine kinase 2, 208

N. diseases: 264; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.260 Biomarker disease BEFREE In stark contrast, Akt2 and Akt3 showed strong progression potential with 78% and 97% of tumors diagnosed as HGG, respectively. 25737557 2015
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.260 Biomarker disease BEFREE Akt2 and Akt3 play a pivotal role in malignant gliomas. 20167810 2010
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.260 Biomarker disease BEFREE Akt2 may play a critical role in the development of gliomas and present a potential therapeutic target for malignant gliomas. 20116920 2010
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.260 AlteredExpression disease BEFREE AKT2 expression is associated with glioma malignant progression and required for cell survival and invasion. 20514445 2010
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.260 Biomarker disease RGD Reduction of Akt2 inhibits migration and invasion of glioma cells. 19330838 2009
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.260 Biomarker disease BEFREE The effects of antisense AKT2 RNA on the inhibition of malignant glioma cell growth in vitro and in vivo. 16402276 2006
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.260 Biomarker disease BEFREE PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas. 15735908 2005