AKT2, AKT serine/threonine kinase 2, 208

N. diseases: 264; N. variants: 18
Disease: Colon Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.040 Biomarker disease BEFREE Taken together, the present results suggest that the targeting effects of resveratrol to AKT1 and AKT2 may be a potent strategy for chemoprevention or therapy for colon cancer. 30387805 2019
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.040 Biomarker disease BEFREE Moreover, our results suggest that both AKT2 and HK2 may be potential targets for the treatment of colon cancer. 30877036 2019
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.040 Biomarker disease BEFREE Taken together, these results demonstrate a role for both AKT1 and AKT2 in radiotherapy response in colon cancer cells involving DNA repair capacity through the nonhomologous end joining pathway, thus suggesting that AKT in combination with DNA-PKcs inhibition may be used for radiotherapy sensitizing strategies in colon cancer. 24338765 2014
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.040 Biomarker disease BEFREE HT-29 human colon cancer cell proliferation is regulated by cytosolic phospholipase A(2)α dependent PGE(2)via both PKA and PKB pathways. 22728329 2012