ESAT, esterase activator, 2096

N. diseases: 23; N. variants: 0
Disease: Active tuberculosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 Biomarker disease BEFREE The purpose of this study was to investigate the factors affecting quantified spot-forming cells (SFCs) to early secreted antigenic target 6 kDa (ESAT-6) or culture filtrate protein 10 kDa (CFP-10) in patients with active tuberculosis. 31357953 2019
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 AlteredExpression disease BEFREE In addition, we compared the levels of A antigen (ESAT-6) and B antigen (CFP-10) in active TB. 28345545 2017
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 GeneticVariation disease BEFREE In patients with positive ELISpot in pleural fluid (n = 16), the PPV for TB was 85.7%, which increased to 91.7% for the ESAT-6 panel and 92.3% for the CFP-10 panel after the introduction of a cut-off >1.0 for the ratio between the pleural fluid and blood interferon-gamma responses. 28024452 2017
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 AlteredExpression disease BEFREE Compared with healthy controls, the levels of ESAT-6 and Ag85B were higher in patients with active tuberculosis (p<0.001). 28416440 2017
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 Biomarker disease BEFREE Thus, our study indicates that the fusion protein CFP-10-ESAT-6-PPE68' may be useful as an immunodominant antigen for the serodiagnosis of active TB. 22357648 2012
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 Biomarker disease BEFREE Thus, ESAT-6 is a potential candidate for use in detection of early, as well as active, tuberculosis and for control of the disease. 10992526 2000