Disease: Autoimmune Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.160 Biomarker group BEFREE The results of our study suggest that miR-326 may target the Ets-1 protein to contribute to iodide-induced thyroiditis, providing a new theoretical basis for the use of miRNA targeting therapy for the treatment of autoimmune diseases. 29181619 2018
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.160 GeneticVariation group BEFREE Notable hypomethylated genes included ETS1, a genetic risk locus for SLE, and PTPN2, a genetic risk locus for other autoimmune diseases. 30471352 2018
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.160 Biomarker group BEFREE Loss of Ets1 leads to premature B cell differentiation into antibody-secreting cells (ASCs), secretion of autoantibodies, and development of autoimmune disease. 28439269 2017
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.160 Biomarker group BEFREE Increasing evidence indicates that ETS-1 could contribute to the pathogenesis of autoimmune disease. 26241881 2015
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.160 Biomarker group BEFREE Several recent studies have implicated ETS1 as a critical driver of immune cell function and differentiation, and mice deficient in ETS1 develop an SLE-like autoimmunity. 25865496 2015
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.160 Biomarker group BEFREE ETS1 is a negative regulator of the Th17 differentiation gene and plays a central role in the pathogenesis of autoimmune diseases. 24708692 2014
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.160 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011