|
Hepatic Encephalopathy
|
0.090 |
AlteredExpression
|
disease |
BEFREE |
This study aimed to explore the association of serum ALB level with the development of overt HE and HE-associated mortality during hospitalization.
|
31636711 |
2019 |
|
Hepatic Encephalopathy
|
0.090 |
Biomarker
|
disease |
BEFREE |
In the competing risk analysis, both intermediate- (subhazard ratio (sHR) 2.01 (95% CI 1.00-4.14); P = .048) and high-risk groups (sHR 4.67 (95% CI 2.19-9.98); P = .0001) were associated with the first HE episode, together with age and albumin.
|
31729816 |
2019 |
|
Hepatic Encephalopathy
|
0.090 |
Biomarker
|
disease |
BEFREE |
Analysing separately the causes of inpatient admission, patients treated with albumin showed a reduction in the incidence of overt hepatic encephalopathy, ascites, spontaneous bacterial peritonitis (SBP) and non-SBP infections.
|
30230204 |
2019 |
|
Hepatic Encephalopathy
|
0.090 |
Biomarker
|
disease |
BEFREE |
Biochemical analysis of the blood revealed hyperammonemia, increases in liver enzymes, and a decrease in albumin indicating liver damage and induction of cirrhotic HE.
|
31173796 |
2019 |
|
Hepatic Encephalopathy
|
0.090 |
Biomarker
|
disease |
BEFREE |
Our retrospective study also suggested that albumin infusion improved the outcomes of cirrhotic patients regardless of overt HE.
|
31596729 |
2019 |
|
Hepatic Encephalopathy
|
0.090 |
Biomarker
|
disease |
BEFREE |
On multivariate analysis, shunt size > 8 mm (p = 0.001), history of HE prior to TIPS (p = 0.006), and low serum albumin (≤ 2.5 g/dL) (p = 0.022) remained independent predictors of RHE, controlling for age and Model for End-Stage Liver Disease score.
|
29872892 |
2018 |
|
Hepatic Encephalopathy
|
0.090 |
Biomarker
|
disease |
BEFREE |
Total bilirubin, albumin and hepatic encephalopathy were independent prognostic markers of survival.
|
30367628 |
2018 |
|
Hepatic Encephalopathy
|
0.090 |
Biomarker
|
disease |
BEFREE |
In prospective randomized controlled trial, 120 patients with overt HE were randomized in two groups: group A lactulose plus albumin (n = 60) and group B lactulose alone (n = 60).
|
27885712 |
2017 |
|
Hepatic Encephalopathy
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
The univariate analysis showed gastrointestinal hemorrhage (P < 0.001), hepatic encephalopathy (P < 0.001), albumin <30 g/L (P < 0.037), creatinine (Cr) >175 µmol/L (P < 0.001), cholinesterase(ChE) activity <3000 U/L (P = 0.019), white blood cell count ≥10 000 (109/L) (P = 0.018), neutrophils ≥80% (P = 0.018), C-reactive protein (CRP) ≥25 mg/L (P < 0.001), procalcitonin ≥1.0 ng/mL (P = 0.007), Child-Pugh class C (P < 0.001), septicemia (P < 0.001), pulmonary infection (P < 0.001),multi-site infection (P = 0.001), acute-on-chronic liver failure (ACLF) (P < 0.001), and advanced hepatocellular carcinoma (HCC) (P < 0.001).
|
28249358 |
2017 |