An insight into the inhibition of fibrillation process verses disaggregation of preformed fibrils of bovine serum albumin by isoprenaline hydrochloride.
Accordingly, serum albumin glycation and fibrillation were accelerated and intensified in the presence of liposomes through a hypothesized glycation-peroxidation loop (GPL).
The qualitative and quantitative aspects of the interactions of the surfactant sodium dodecyl sulphate (SDS) and antiinflammatory drug diclofenac sodium (DCF) with human serum albumin at different stages of the fibrillation process have been studied employing a combination of spectroscopic, calorimetric, and microscopic techniques.
Fibrillation studies using Congo red (CR), Thioflavin T (ThT) and Tryptophan emission (Trp) assay have suggested the promoting role of CeO<sub>2</sub>NPs against HSAfibrillation.
We used nuclear magnetic resonance, circular dichroism, and fluorescence spectroscopies to characterize the structure and fibrillation of α-synuclein, an intrinsically disordered protein implicated in Parkinson's disease, using Ficoll70, its monomer sucrose and bovine serum albumin as crowding agents.
Our work aims to open new perspectives as far as the binding of flavonoids to HSA are concern and shows as the properties of both compounds can be remarkable modified after the complex formation, resulting, for instance, in a protein structure much more resistant to oxidation and fibrillation.
Inhibiting the Fibrillation of Serum Albumin Proteins in the Presence of Surface Active Ionic Liquids (SAILs) at Low pH: Spectroscopic and Microscopic Study.