|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
Lower albumin was also associated with increased levels of several inflammatory biomarkers, markers of liver fibrosis, albuminuria, and greater arterial stiffness, diastolic dysfunction and pulmonary hypertension.
|
31843232 |
2020 |
|
Fibrosis, Liver
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
However, the best effect was the combined effect of doxazosin, carvedilol, and curcumin, reversing liver fibrosis and decreasing the amount of collagen I (Sirius red stain) without affecting the morphology of hepatocytes (hematoxylin and eosin stain), showing normal hepatic function (glucose, albumin, AST, ALT, total bilirubin, and total proteins).
|
31183386 |
2019 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
The S-index calculated from γ-glutamyl transpeptidase, albumin, and platelets is reported to predict the severity of liver fibrosis.
|
30679923 |
2019 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
The results of the present study indicate that alteration of trace elements during pathogenesis of hepatic fibrosis is due to metabolic imbalance, biochemical abnormalities, decreased serum albumin, and ascites following NDMA-induced liver injury.
|
30679730 |
2019 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
In the current study, 12 commonly used preoperative serological indicators from 161 HCC patients with different degree of liver fibrosis were collected retrospectively, and 8 of the indicators (ALB, PA, TBil, INR, AST, GGT, ALP, and PT) were ultimately used in matter-element analysis to create a formula.
|
30867373 |
2019 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
Monitoring aminotransferase and albumin is suggested in the guidelines, unfortunately this method is unreliable for detecting liver fibrosis.
|
30565876 |
2019 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
In univariate analysis, albumin, prothrombin time, prealbumin, cholinesterase and RBP were significantly altered in those with encephalopathy (p < 0.01), but only prealbumin, cholinesterase and RBP levels were significant predictors in multivariate analysis, and each was linked to the severity of liver fibrosis defined by the Child-Pugh score (all p < 0.001).
|
30392460 |
2019 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
Albumin-Bilirubin Score Differentiates Liver Fibrosis Stage and Hepatocellular Carcinoma Incidence in Chronic Hepatitis B Virus Infection: A Retrospective Cohort Study.
|
31115300 |
2019 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
After 4 weeks of intravenous tail vein injection into CCl<sub>4</sub>-injured mouse liver, LEPCs engrafted into liver parenchyma, differentiated into ALB positive hepatocytes, and could alleviate liver fibrosis through down regulating fibrosis genes-Tgfb1 and α-SMA as well as decreasing expression of collagen gene Col1a1, Col3a1, and Col4a1, and regain liver function by recovering ALT and AST.
|
28625011 |
2018 |
|
Fibrosis, Liver
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In vivo anti-liver fibrotic activity of EDQ was assessed using CCl<sub>4</sub> induced liver fibrosis in Wistar rats and serum biochemical parameters (AST, ALT, ALP, SB, cholesterol), MDA, PT, INR, GSH, SOD, CAT, liver glycogen, serum albumin levels were monitored. qRT-PCR analysis of TNF-α, COX-2, iNOS were performed.
|
29174446 |
2018 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
Low PrC function correlated with markers of liver dysfunction and inflammation: INR(r = -.72, P < .001), bilirubin (r = -.620, P < .001), albumin (r = .539, P < .001), creatinine (r = -.417, P < .001), ferritin (r = -.68, P = .035), procalcitonin (r = -.79, P = .01), raised ESR (r = .56, P < .001) and liver fibrosis (r = -.840, P < .001).
|
29704446 |
2018 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
A simple non-invasive score (Fibrofast, FIB-5) was developed using five routine laboratory tests (ALT, AST, alkaline phosphatase, albumin and platelets count) for the detection of significant hepatic fibrosis in patients with chronic hepatitis C. The FIB-4 index is a non-invasive test for the assessment of liver fibrosis, and a score of ≤1.45 enables the correct identification of patients who have non-significant (F0-1) from significant fibrosis (F2-4), and could avoid liver biopsy.
|
28425016 |
2017 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
In a carbon tetrachloride (CCl4)-induced HF rat model, we observed that NTSD and TSP had similar effects on the improvement of liver functions in rats, including a decrease in serum alanine amino transferase (ALT) and aspartate amino transferase (AST) serum concentrations and increased albumin content in addition to a marked attenuation of CCl4-induced liver damage and fibrosis.
|
27633729 |
2016 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
Fusion protein of retinol-binding protein and albumin domain III reduces liver fibrosis.
|
25864124 |
2015 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
However, there was no correlation of serum miR-210 levels with parameters of liver function including serum albumin, international normalized ratio and bilirubin, as well as the stages of liver fibrosis.
|
26319884 |
2015 |
|
Fibrosis, Liver
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Comparative analysis between HCV-2 and HCV-3 showed a younger age (p=0.002), less prevalence of arterial hypertension (p=0.03), higher serum albumin levels (p=0.01), more advanced stage of liver fibrosis (p=0.03), and higher frequency of steatosis in patients with HCV-3 (p=0.001).
|
24861286 |
2014 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
CTD_human |
The value of serum ischemia-modified albumin for assessing liver function in patients with chronic liver disease.
|
21851314 |
2011 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
BEFREE |
Serum Se levels significantly declined in proportion to the severity of hepatic fibrosis and were positively correlated with serum albumin (r = 0.372, P = .0065) and zinc (r = 0.403, P = .0081) concentrations.
|
22118753 |
2011 |
|
Fibrosis, Liver
|
0.400 |
Biomarker
|
disease |
CTD_human |
[Apolipoprotein A in patients with alcoholic liver disease].
|
17977396 |
2008 |
|
Fibrosis, Liver
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In humans, serum albumin levels correlated with albumin mRNA content as indicated by the intensity of dot blot hybridization and Type I procollagen mRNA levels correlated with the activity of liver fibrosis.
|
3804213 |
1987 |