ALB, albumin, 213

N. diseases: 1198; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 Biomarker phenotype BEFREE Patients with acute decompensated cirrhosis were given albumin infusions at 10 hospitals in the United Kingdom. 31446184 2019
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 Biomarker phenotype BEFREE For these reasons, we favor albumin administration to patients with decompensated cirrhosis wait-listed for liver transplantation. 30346096 2019
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 Biomarker phenotype BEFREE Because ACLF patients have greater hemodynamic derangements than patients with decompensated cirrhosis, we investigated whether PICD could develop with modest-volume paracentesis (MVP) and the role of albumin infusion. 31849085 2019
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 Biomarker phenotype BEFREE These effects might be responsible for the beneficial effects of albumin therapy on outcomes of patients with decompensated cirrhosis. 30905652 2019
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 AlteredExpression phenotype BEFREE Serum albumin levels (per mg/dL; HR: 0.83, 95% CI: 0.77-0.89, P < 0.001) and MELD-Na (per point; HR: 1.15, 95% CI: 1.04-1.28, P = 0.006) in cACLD and MELD-Na (per point; HR: 1.12, 95% CI: 1.05-1.19, P < 0.0001) in DC patients were the only parameters independently associated with first and further hepatic decompensation, respectively. 30107095 2019
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 AlteredExpression phenotype BEFREE We identified 5 baseline factors (body mass index, encephalopathy, ascites, and serum levels of alanine aminotransferase and albumin) associated with a reduction of CPT score to class A in patients with hepatitis C virus-associated decompensated cirrhosis receiving DAA therapy. 29535028 2018
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 Biomarker phenotype BEFREE Oxidized Albumin Triggers a Cytokine Storm in Leukocytes Through P38 Mitogen-Activated Protein Kinase: Role in Systemic Inflammation in Decompensated Cirrhosis. 30070728 2018
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 Biomarker phenotype BEFREE Long-term albumin administration in decompensated cirrhosis (ANSWER): an open-label randomised trial. 29861076 2018
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 GeneticVariation phenotype BEFREE Compensated cirrhosis (odds ratio [OR] compared to decompensated cirrhosis, 2.41; 95% CI, 1.16-5.02), albumin ≥ 3.5 g/dL (OR, 3.15; 95% CI 1.46-6.80), or total bilirubin ≤ 1.2 mg/dL (OR 3.34; 95% CI, 1.59-7.00) were associated with SVR12. 29306043 2018
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 Biomarker phenotype BEFREE Patients with decompensated cirrhosis admitted to the hospital with a serum albumin of <30 g/L are eligible, subject to exclusion criteria. 30344180 2018
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 GeneticVariation phenotype BEFREE The critically ill patient with decompensated cirrhosis has a unique physiology and alterations in albumin that need to be understood to properly resuscitate them and minimize morbidity and mortality. 29132516 2017
CUI: C1619727
Disease: Decompensated cirrhosis of liver
Decompensated cirrhosis of liver
0.100 AlteredExpression phenotype BEFREE Taken together, human albumin solution infusions may be used to reduce circulating PGE2 levels, attenuating immune suppression and reducing the risk of infection in patients with acutely decompensated cirrhosis or ESLD. 24728410 2014