Disease: Acute monocytic leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.060 AlteredExpression disease BEFREE Accumulating studies have proved EZH2 dysregulation mediated by mutation and expression in diverse human cancers including AML. 31794134 2020
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.060 Biomarker disease BEFREE Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML. 30890554 2019
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.060 Biomarker disease BEFREE Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase. 28678185 2017
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.060 GeneticVariation disease BEFREE AML with LM-CH was found in 40 patients (23%) and was associated with clonal hematopoiesis of indeterminate potential years before AML, older age, secondary AML and more frequent MDS-type co-mutations (TET2, RUNX1 and EZH2). 27881874 2017
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.060 GeneticVariation disease BEFREE EZH2 mutations were identified in 13/714 (1.8%) of AML patients were found to be more common in males (P = 0.033). 23613835 2013
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.060 GeneticVariation disease BEFREE These data suggest ASXL1 mutations might results in dominance of the mutant clone in Chinese with MDS whereas EZH2 mutations might predict an increased risk of transformation to AML. 23099237 2013