F2, coagulation factor II, thrombin, 2147

N. diseases: 490; N. variants: 42
Disease: Vascular Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042373
Disease: Vascular Diseases
Vascular Diseases 		0.020 GeneticVariation group BEFREE We analyzed the prevalence of F2 20210A and F5 1691A alleles in 336 patients with documented PAOD at Fontaine stage II-IV and 300 controls without vascular disease. 10669148 2000
CUI: C0042373
Disease: Vascular Diseases
Vascular Diseases 		0.020 GeneticVariation group BEFREE In view of recent reports of an increased risk for ischemic cerebral vascular disease in patients with the prothrombin 20210A mutation, we suggest that many of the reported cases of ischemic stroke and protein C deficiency may have had additional prothrombotic disorders such as the prothrombin mutation. 9890720 1998