F2R, coagulation factor II thrombin receptor, 2149

N. diseases: 347; N. variants: 10
Disease: Peripheral arterial stenosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4025272
Disease: Peripheral arterial stenosis
Peripheral arterial stenosis 		0.020 Biomarker disease BEFREE A triple antiplatelet therapy with a cyclooxygenase-1 (COX-1) inhibitor, a P2Y<sub>12</sub> receptor antagonist, and a protease-activated receptor-1 (PAR-1) antagonist has been established in the secondary prevention of atherothrombosis in patients with acute myocardial infraction and in those with peripheral artery disease. 30039419 2018
CUI: C4025272
Disease: Peripheral arterial stenosis
Peripheral arterial stenosis 		0.020 Biomarker disease BEFREE Vorapaxar is a direct inhibitor of PAR-1 and the only agent of this class approved for the prevention of recurrent ischemic events in patients with prior myocardial infarction or peripheral artery disease. 28565918 2018