F3, coagulation factor III, tissue factor, 2152

N. diseases: 456; N. variants: 10
Disease: Atherothrombosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1963943
Disease: Atherothrombosis
Atherothrombosis 		0.070 AlteredExpression disease BEFREE Wog targeting pathological TF expression without affecting its basal level may be a safer templet in the development of anticoagulant agent for cardiovascular thrombotic diseases related to atherothrombosis. 31265843 2019
CUI: C1963943
Disease: Atherothrombosis
Atherothrombosis 		0.070 Biomarker disease BEFREE Hence, the present study explored the potential link between IL-1β, NETs, and tissue factor (TF)-the key trigger of the coagulation cascade-in atherothrombosis. 31779200 2019
CUI: C1963943
Disease: Atherothrombosis
Atherothrombosis 		0.070 Biomarker disease BEFREE In TF-overexpressing apolipoprotein (E)-deficient (ApoE-/-) mice, 67% (8 of 12) of carotid plaques exhibited plaque disruption and atherothrombosis. 30500376 2019
CUI: C1963943
Disease: Atherothrombosis
Atherothrombosis 		0.070 AlteredExpression disease BEFREE We investigated the role of anti-apoA-1 IgG on tissue factor (TF) expression and activation, a key coagulation regulator underlying atherothrombosis. 27356567 2016
CUI: C1963943
Disease: Atherothrombosis
Atherothrombosis 		0.070 Biomarker disease BEFREE Although the extrinsic (tissue factor-factor VIIa [FVIIa]) pathway is considered as a major trigger of coagulation in atherothrombosis, the role of the intrinsic coagulation pathway via coagulation FXII herein is unknown. 24855058 2014
CUI: C1963943
Disease: Atherothrombosis
Atherothrombosis 		0.070 AlteredExpression disease BEFREE Caspase-3 and tissue factor expression in lipid-rich plaque macrophages: evidence for apoptosis as link between inflammation and atherothrombosis. 15078795 2004
CUI: C1963943
Disease: Atherothrombosis
Atherothrombosis 		0.070 Biomarker disease BEFREE Vastatins inhibit tissue factor in cultured human macrophages. A novel mechanism of protection against atherothrombosis. 9081680 1997