F11, coagulation factor XI, 2160

N. diseases: 100; N. variants: 139
Disease: Hypertensive disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.310 Biomarker group BEFREE Our results outline a coagulation-inflammation circuit that promotes vascular dysfunction, and highlight the possible utility of FXI-targeted anticoagulants in treating hypertension, beyond their application as antithrombotic agents in cardiovascular disease. 28148841 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.310 Biomarker group CTD_human The contact phase of blood coagulation and renin activation in essential hypertension before and after captopril. 6383834 1984