F13A1, coagulation factor XIII A chain, 2162

N. diseases: 117; N. variants: 72
Disease: Ischemic stroke ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 GeneticVariation disease BEFREE A total of nine gene variants/polymorphisms - F5 (Leiden - R5 06Q, rs6025), F2 (20210G > A, rs1799963), F13A1 (rs5985" genes_norm="2162">V34L, rs5985), MTHFR (677C > T - rs1801133;rs771406104;rs1455404812;s771406104" genes_norm="1636;2244;4524">A222V, rs1801133), MTHFR (1298A > C - rs1801131" genes_norm="4524">E429A, rs1801131), FGB (-455G > A -c.-463G > A; rs1800790), SERPINE1 (PAI14G/5G - rs1799889), ACE (ACE I/D, rs1799752), ITGB3 (GPIIIa L33P, rs5918) and the APOE E2/E3/E4 alleles (rs7412, rs429358) - were genotyped in 200 newly diagnosed ischemic stroke (IS) patients, 165 patients with ischemic coronary heart disease (CHD) and 159 controls with no cerebroor cardiovascular disease (non-CVD). 27629735 2016
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 GeneticVariation disease BEFREE In conclusion, the F13A1 204Phe allele was strongly associated with ischemic stroke in young women. 18006701 2008
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 GeneticVariation disease BEFREE Heterozygosity for factor XIIIA Phe204 was associated with a milder increased risk of ischaemic stroke, and analysis of a kindred with congenital dysfibrinogenaemia suggested that co-inheritance of the factor XIIIA Phe204 allele may increase susceptibility to ischaemic stroke. 11841441 2002