|
Diabetes
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Multiple logistical regression analyses indicated no correlation between ALDH2 genotype and the occurrence of restenosis after PCI (OR = 1.448, 95% CI: 0.965-2.168, p = 0.073), though a significant association was observed for patients with diabetes (OR = 4.053, 95% CI: 1.668-10.449, p = 0.003).
|
31345174 |
2019 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Only after treadmill running, but not at rest, we found a significant decrease in % fractional shortening and % ejection fraction in ALDH2*2 mice with diabetes compared to C57BL/6 diabetic mice as well as non-diabetic (control) ALDH2*2 mice.
|
29677191 |
2018 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Targeting FA and its metabolizing enzyme ALDH2 may be a valid approach for preventing and treating dementia in diabetes mellitus.-Tan, T., Zhang, Y., Luo, W., Lv, J., Han, C., Hamlin, J. N. R., Luo, H., Li, H., Wan, Y., Yang, X., Song, W., Tong, Z. Formaldehyde induces diabetes-associated cognitive impairments.
|
29401634 |
2018 |
|
Diabetes
|
0.100 |
PosttranslationalModification
|
disease |
BEFREE |
ALDH2 deficiency potentiates oxidative stress and AMPK phosphorylation induced by diabetes via post-translational regulation of LKB1.
|
27488451 |
2016 |
|
Diabetes
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The faster metabolism of ethanol and acetaldehyde by the ADH1B*2 allele and ALDH2*1/*1 genotype and higher ketosis levels were associated with higher UA levels in alcoholics, while diabetes and the consumption of sake were negative determinants.
|
26542604 |
2016 |
|
Diabetes
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Significant interactions were observed between alcohol and ADH1b (rs1229984) with respect to LDL and between alcohol and ALDH2 (rs886205) with respect to IGT/diabetes.
|
20700531 |
2010 |
|
Diabetes
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In total, 515 subjects were examined for the association of ALDH2 genotype with inheritance of diabetes.
|
15563966 |
2004 |
|
Diabetes
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Therefore, we hypothesized that expression of different ALDH2 and ADH2 polymorphisms may induce differences in vascular complications in diabetes and conducted two studies.
|
15318096 |
2004 |
|
Diabetes
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Thus, this association of ALDH2 genotype with DM-Mt3243 provides insight into the etiology of diabetes in the mitochondrial diseases.
|
8941476 |
1996 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
We conclude that maternal inheritance of diabetes was common in the inactive ALDH2 group.
|
8877297 |
1996 |