FANCG, FA complementation group G, 2189

N. diseases: 132; N. variants: 19
Disease: Malignant neoplasm of pancreas ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.060 GeneticVariation disease BEFREE BRCA2, FANCC, and FANCG gene mutations are present in a subset of pancreatic cancer. 16243825 2005
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.060 GeneticVariation disease BEFREE Two truncating FANCC mutations but no truncating FANCG mutations were identified in young onset (<55 years) pancreatic cancer cases with no family history of pancreatic cancer. 15695377 2005
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.060 Biomarker disease BEFREE Recently, several sequence changes in FANCC and FANCG were reported in pancreatic cancer. 15277238 2004
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.060 GeneticVariation disease BEFREE The Fanconi genes BRCA2, FANCC and FANCG are mutated in a subset of pancreatic cancer. 15107617 2004
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.060 GeneticVariation disease BEFREE These and published data suggest the possibility that although germline and somatic mutations in FANCC and FANCG may contribute to the occurrence of pancreatic cancers, the pancreatic cancers that arise do so in an apparent sporadic fashion rather than with a phenotype of familial pancreatic cancer. 14726700 2004
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.060 GeneticVariation disease BEFREE Here we report inherited and somatic mutations of FANCC and FANCG present in young-onset pancreatic cancer. 12750283 2003