FASN, fatty acid synthase, 2194

N. diseases: 245; N. variants: 6
Disease: Malignant neoplasm of stomach ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.040 Biomarker disease BEFREE Knockdown of FASN suppressed GC cell proliferation and metastasis <i>in vitro</i>. 29928446 2018
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.040 Biomarker disease BEFREE Bioinformatic analysis revealed that MACC1 is positively associated with fatty acid synthase (FASN), a major enzyme of lipogenesis, and drives chemoresistance to oxaliplatin in GC. 28339092 2017
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.040 Biomarker disease BEFREE Taken together, it was suggested that FASN was closely associated with GC metastasis and survival, which further provided evidence that FASN may be a promising prognostic biomarker for patients with GC. 26936091 2016
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.040 Biomarker disease BEFREE The frequency of FASN gene amplification was also significantly higher in gastric cancer than in adjacent normal tissue. 26514456 2015