FASN, fatty acid synthase, 2194

N. diseases: 245; N. variants: 6
Disease: Tuberculosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 Biomarker disease BEFREE In Mycobacterium tuberculosis, acyl carrier protein (AcpM)-mediated fatty acid synthase type II is integral for the synthesis of mycolic acids. 30847903 2019
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 Biomarker disease BEFREE Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 Å resolution. 30250274 2018
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 Biomarker disease BEFREE The site of action of isoniazid, used in the treatment of tuberculosis for 50 years, and the consumer antimicrobial agent triclosan were revealed recently to be the enoyl-ACP reductase of the type II FAS. 11591436 2001