MPEG1, macrophage expressed 1, 219972

N. diseases: 98; N. variants: 0
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.020 Biomarker disease BEFREE A previous study identified a novel gene, monopolar spindle protein kinase 1 (Mps1), a downstream target of BRAF<sup>V600E</sup> only, rather than of wild-type BRAF as well, which contributes to tumorigenesis in melanoma. 30854056 2019
CUI: C0025202
Disease: melanoma
melanoma 		0.020 PosttranslationalModification disease BEFREE Phosphorylation of Mps1 by BRAFV600E prevents Mps1 degradation and contributes to chromosome instability in melanoma. 22430208 2013