FCGR3B, Fc fragment of IgG receptor IIIb, 2215

N. diseases: 291; N. variants: 8
Disease: Degenerative polyarthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.040 Biomarker disease BEFREE Moreover, anti-CD16/32 antibody (Ab) modification could prolong the retention time of NPs in knee joints of OA mice with anterior cruciate ligament transection (ACLT). 31849213 2020
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.040 AlteredExpression disease BEFREE Monocytes from OA participants had elevated expression of the activation markers CD16, CCR2, and HLA-DR and induced greater production of tumor necrosis factor (TNF) and IL-1β compared to healthy controls. 29128509 2018
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.040 AlteredExpression disease BEFREE The presence of the CD56(+)<sup>bright</sup>CD16(-) cells expressing granzyme A correlated with increased levels of pro-inflammatory cytokines in synovial fluid from OA patients. 28668542 2017
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.040 AlteredExpression disease BEFREE Immunohistochemical examinations revealed higher levels of FCGR3B and LILRB3 and lower level of SOX-9 in OA menisci. 25525593 2014