FCGR3B, Fc fragment of IgG receptor IIIb, 2215

N. diseases: 291; N. variants: 8
Disease: Primary Sjögren's syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151449
Disease: Primary Sjögren's syndrome
Primary Sjögren's syndrome 		0.030 GeneticVariation disease BEFREE Copy number variations of FCGR3B are associated with several immune related diseases such as systemic lupus erythematosus, rheumatoid arthritis and primary Sjögren's syndrome. 25012234 2014
CUI: C0151449
Disease: Primary Sjögren's syndrome
Primary Sjögren's syndrome 		0.030 Biomarker disease BEFREE Among patients with pSS in our cohort, low FCGR3B CN was not associated with anti-Ro ± La autoantibodies, but was associated with lower rheumatoid factor titers (p = 0.001) and serum IgG levels (p = 0.031). 22942264 2012
CUI: C0151449
Disease: Primary Sjögren's syndrome
Primary Sjögren's syndrome 		0.030 Biomarker disease BEFREE FCGR3B copy number < or >2 was associated with an increased risk of SLE and primary SS but not RA. 19741716 2010