FCGR3B, Fc fragment of IgG receptor IIIb, 2215

N. diseases: 291; N. variants: 8
Disease: Lupus Erythematosus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.040 Biomarker disease BEFREE The inflammation intensity in the liver decreased with IgG depletion and the lupus IgG-induced liver inflammation in FcγRIII-deficient mice was comparatively low; while, inflammation was increased in FcγRIIb-deficient mice. 29988500 2018
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.040 Biomarker disease BEFREE The apoptosis of neutrophils induced by lupus IgG is related to FcγRIII and Fas/Fas ligand pathways. 29450882 2018
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.040 Biomarker disease BEFREE FCGR3B copy number loss rather than gain is a risk factor for systemic lupus erythematous and lupus nephritis: a meta-analysis. 24673810 2015
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.040 AlteredExpression disease BEFREE To clarify the role played by Fkn in the development of glomerular lesions in lupus nephritis, we examined Fkn expression and CD16(+) Mo accumulation induced in experimental C.B-17/Inc-scid/scid (SCID) lupus model mice by injection of IgG(3)-producing hybridoma clones obtained from MRL/lpr mice. 20410215 2010