FCGR3B, Fc fragment of IgG receptor IIIb, 2215

N. diseases: 291; N. variants: 8
Disease: Granulomatosis with polyangiitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3495801
Disease: Granulomatosis with polyangiitis
Granulomatosis with polyangiitis 		0.320 AlteredExpression disease BEFREE We found no significant difference in the degree of maturation of PMNs from GPA patients (n = 8) and healthy controls (n = 11) as determined from cell surface expression of the neutrophil maturation marker CD16 and gene expression profile of FCGR3B. 27755585 2016
CUI: C3495801
Disease: Granulomatosis with polyangiitis
Granulomatosis with polyangiitis 		0.320 Biomarker disease BEFREE Here we report strong association between FCGR3B copy number and risk of systemic lupus erythematosus (P = 2.7 x 10(-8)), microscopic polyangiitis (P = 2.9 x 10(-4)) and Wegener's granulomatosis in two independent cohorts from the UK (P = 3 x 10(-3)) and France (P = 1.1 x 10(-4)). 17529978 2007
CUI: C3495801
Disease: Granulomatosis with polyangiitis
Granulomatosis with polyangiitis 		0.320 Biomarker disease CTD_human Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. 16482158 2006