FCN2, ficolin 2, 2220

N. diseases: 159; N. variants: 11
Disease: Rheumatic Fever ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0035436
Disease: Rheumatic Fever
Rheumatic Fever 		0.020 GeneticVariation disease BEFREE In addition, the FCN2 GG and AG genotypes in the -4 position were also found to be protective factors for the development of RF and for carditis respectively (OR = 3.32, CI: 1.066-10.364; OR = 0.15, 95% CI: 0.037-0.566). 28576308 2017
CUI: C0035436
Disease: Rheumatic Fever
Rheumatic Fever 		0.020 GeneticVariation disease BEFREE Here we investigated polymorphisms in the promoter region of the FCN2 gene (at positions -986/-602 and +4) in 122 patients with RF and CRHD and in 210 healthy subjects from the same geographic region and socioeconomic background. 19664148 2009