FEN1, flap structure-specific endonuclease 1, 2237

N. diseases: 113; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.320 Biomarker group CTD_human FEN1 promotes tumor progression and confers cisplatin resistance in non-small-cell lung cancer. 28371273 2017
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.320 AlteredExpression group BEFREE Our data show a clear overexpression of FEN1 in 19/25 samples from testicular tumors (mostly seminomas) and 4/4 samples from lung tumors (non-small cell lung cancer). 19596913 2009
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.320 GeneticVariation group LHGDN Increased expression and no mutation of the Flap endonuclease (FEN1) gene in human lung cancer. 14562054 2003