FGF3, fibroblast growth factor 3, 2248

N. diseases: 200; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.040 Biomarker disease BEFREE Generalized down-regulation of miRs, including those that target the fibroblast growth factor 3 pathway, such as miR-145, miR-101, miR-100, and miR-99a, has been observed in low-grade, non-muscle invasive BC. 23911686 2014
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.040 GeneticVariation disease BEFREE Mutations in fibroblast growth factor 3 receptor (FGFR3) are frequent events in low-grade bladder tumors. 12910517 2003
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.040 Biomarker disease BEFREE Thus cyclin D1 and EMS1, but not FGF3 and FGF4, are likely to play a pathogenic role in the 11q13 amplification in bladder cancer. 8622895 1996
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.040 Biomarker disease BEFREE None of 37 hematopoietic neoplasms, one out of 13 melanomas (8%), three out of 43 bladder tumors (7%) and 41 out of 238 breast carcinomas (17%) contained amplified FGF-related sequences, namely HST and INT2. 2474139 1989