FGF10, fibroblast growth factor 10, 2255

N. diseases: 152; N. variants: 28
Disease: Penile hypospadias ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1691215
Disease: Penile hypospadias
Penile hypospadias 		0.030 Biomarker disease BEFREE Patients with hypospadias consistently showed aberrant immunohistochemical staining patterns for FGF8/FGF10/FGFR2 in epidermis and dermis compared to patients without penile malformation (p < 0.01 for all markers). qPCR displayed no difference in expression levels on mRNA level (FGFR2 p = 0.44, FGF8 p = 0.77, and FGF10 p = 0.17) comparing normal foreskin with foreskin from patients with hypospadias.Figure. 31718875 2019
CUI: C1691215
Disease: Penile hypospadias
Penile hypospadias 		0.030 Biomarker disease BEFREE FGFR2, FGF8, FGF10 and BMP7 as candidate genes for hypospadias. 17264867 2007
CUI: C1691215
Disease: Penile hypospadias
Penile hypospadias 		0.030 GeneticVariation disease BEFREE FGF-10 deficient mutant male mouse revealed normal corporal bodies with failure of the urethral plate to fuse ventrally consistent with hypospadias. 15086024 2004