FGFR1, fibroblast growth factor receptor 1, 2260

N. diseases: 816; N. variants: 119
Disease: Major Depressive Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.330 AlteredExpression disease BEFREE FGFR1 is implicated in synapse formation in the hippocampus, and alterations in the expression of <i>Fgfr1</i> and its ligand, <i>Fgf2</i> accompany major depression. 28439461 2017
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.330 AlteredExpression disease BEFREE While upregulation of FGFR-1 has been previously shown in MDD; abnormalities in GC-1, GRINA, and NRP-1 have not been reported. 23261523 2013
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.330 Biomarker disease PSYGENET While upregulation of FGFR-1 has been previously shown in MDD; abnormalities in GC-1, GRINA, and NRP-1 have not been reported. 23261523 2013
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.330 Biomarker disease PSYGENET These results showed that ErbB3 but not Fgfr1 mRNA levels were reduced in leukocytes of MDD patients compared to healthy subjects. 22989054 2012
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.330 AlteredExpression disease BEFREE These results showed that ErbB3 but not Fgfr1 mRNA levels were reduced in leukocytes of MDD patients compared to healthy subjects. 22989054 2012
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.330 Biomarker disease PSYGENET As a result, 99 genes were listed as the differentially expressed genes in major depression, of which several genes such as FGFR1, NCAM1, and CAMK2A were of interest. 18068248 2008