FGFR3, fibroblast growth factor receptor 3, 2261

N. diseases: 654; N. variants: 55
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.660 AlteredExpression disease BEFREE We describe FGFR3 overexpression in 15% of CRC patients with oligometastatic liver disease as a prognosticator for poor outcome. 30181810 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.660 AlteredExpression disease BEFREE As overexpression of FGFR3 mitigated IRI-induced apoptosis in CRC cell models, this suggests that the drug itself activated a survival response. 28340475 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.660 PosttranslationalModification disease BEFREE Collectively, our findings provide new evidence that PRMT5 plays an important role in CRC pathogenesis through epigenetically regulating arginine methylation of oncogenes such as eIF4E and FGFR3. 26078354 2015
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.660 Biomarker disease BEFREE Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration. 20234367 2010
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.660 GeneticVariation disease BEFREE In addition, the two novel mutations of FGFR3 in colorectal carcinomas were identified. 11325814 2001
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.660 AlteredExpression disease BEFREE Novel transcripts of fibroblast growth factor receptor 3 reveal aberrant splicing and activation of cryptic splice sequences in colorectal cancer. 10945607 2000
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.660 Biomarker disease CTD_human
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.660 GeneticVariation disease UNIPROT
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.660 CausalMutation disease CLINVAR