MMRN1, multimerin 1, 22915

N. diseases: 272; N. variants: 3
Disease: Posterior capsule opacification ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1444680
Disease: Posterior capsule opacification
Posterior capsule opacification 		0.010 Biomarker disease BEFREE Our laboratory has previously shown that AGEs in extracellular matrix (ECM) proteins promote TGFβ2 (transforming growth factor-beta 2)-mediated epithelial-to-mesenchymal transition (EMT) of lens epithelial cells (LECs), which could play a role in fibrosis associated with posterior capsule opacification. 29588342 2018