ATF6, activating transcription factor 6, 22926

N. diseases: 179; N. variants: 30
Disease: Atresia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243066
Disease: Atresia
Atresia 		0.010 Biomarker disease BEFREE Collectively, these results imply that ATF6, as a key player in ER stress signaling, may regulate apoptosis, the cell cycle, steroid hormone synthesis, and other modulators related to folliculogenesis in mouse granulosa cells, which may indirectly be involved in the development, ovulation, and atresia of ovarian follicles by affecting the physiological function of granulosa cells. 28100484 2017