ATF6, activating transcription factor 6, 22926

N. diseases: 179; N. variants: 30
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0598935
Disease: Tumor Initiation
Tumor Initiation
0.020 Biomarker phenotype BEFREE Analysis of nATF6IEC MyD88/TRIF-knockout mice showed that tumor initiation and growth required MyD88/TRIF-dependent activation of signal transducer and activator of transcription 3. 30063920 2018
CUI: C0598935
Disease: Tumor Initiation
Tumor Initiation
0.020 Biomarker phenotype BEFREE The Atf6 pathway was modestly activated only after tumor initiation. 25598862 2015