Disease: Multiple Myeloma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.130 GeneticVariation disease BEFREE One of these (rs3777189-C) co-locates with the best-supported lead variants for ELL2 expression and MM risk, and reduces binding of MAFF/G/K family transcription factors. 29695719 2018
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.130 AlteredExpression disease BEFREE Since ELL2 is critical to the B cell differentiation process, reduced ELL2 expression is consistent with inherited genetic variation contributing to arrest of plasma cell development, facilitating MM clonal expansion. 28903037 2017
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.130 GeneticVariation disease GWASCAT Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci. 28112199 2017
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.130 GeneticVariation disease GWASCAT Genome-wide association study identifies multiple susceptibility loci for multiple myeloma. 27363682 2016
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.130 GeneticVariation disease BEFREE We find that the MM risk allele harbours a Thr298Ala missense variant in an ELL2 domain required for transcription elongation. 26007630 2015
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.130 GeneticVariation disease GWASCAT Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma. 26007630 2015