|
ST segment elevation myocardial infarction
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
High Mon2 levels were associated with lower ejection fraction after STEMI onset (P = 0.001) and at 6-month follow-up (P < 0.001).
|
30644612 |
2019 |
|
Coronary Artery Disease
|
0.020 |
Biomarker
|
disease |
BEFREE |
On multivariate regression, MPAs with Mon2 independently predicted diffuse CAD (odds ratio 1.10, 95% confidence interval 1.02-1.19, P = .01) and correlated negatively with endothelium-dependent microvascular vasodilation (r = -.37, P = .008), an association which persisted after adjustment for covariates.
|
29423944 |
2018 |
|
ST segment elevation myocardial infarction
|
0.020 |
Biomarker
|
disease |
BEFREE |
On the other hand, patients with UAP and STEMI had significantly higher proportions and counts of Mon2 subsets.
|
29047360 |
2017 |
|
Coronary Artery Disease
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Therefore, we examined the relationships between monocyte subsets (CD14<sup>++</sup>CD16<sup>-</sup> "classical - Mon1", CD14<sup>++</sup>CD16<sup>+</sup> "intermediate - Mon2" and CD14<sup>+</sup>CD16<sup>++</sup> "nonclassical - Mon3"), endothelial function and risk factor profiles in 130 patients with CAD undergoing coronary artery bypass grafting.
|
28229168 |
2017 |
|
Heart failure
|
0.010 |
Biomarker
|
disease |
BEFREE |
Abnormal Mon1 and Mon2 phagocytic capacities were related to HF development, but the association was dependent on the infarct size and other prognosticators.
|
30644612 |
2019 |
|
Congestive heart failure
|
0.010 |
Biomarker
|
disease |
BEFREE |
Abnormal Mon1 and Mon2 phagocytic capacities were related to HF development, but the association was dependent on the infarct size and other prognosticators.
|
30644612 |
2019 |
|
Coronary Arteriosclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Impact of Mon2 monocyte-platelet aggregates on human coronary artery disease.
|
29423944 |
2018 |
|
Coronary heart disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
Impact of Mon2 monocyte-platelet aggregates on human coronary artery disease.
|
29423944 |
2018 |
|
Endothelial dysfunction
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Monocyte-platelet aggregates with Mon2 are increased in patients with diffuse CAD and therefore could represent an important contributor to accelerated coronary atherosclerotic progression by a mechanism involving microvascular endothelial dysfunction.
|
29423944 |
2018 |
|
Angina, Unstable
|
0.010 |
Biomarker
|
disease |
BEFREE |
On the other hand, patients with UAP and STEMI had significantly higher proportions and counts of Mon2 subsets.
|
29047360 |
2017 |
|
Thin-cap fibroatheroma
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
In the OCT subgroup, patients with thin-cap fibroatheroma (TCFA) had higher proportions and absolute number of Mon2 (11.96% ± 4.27% vs. 9.42% ± 4.05%, p = 0.034; 5.17 × 104/ml ± 1.92 × 104/ml vs. 3.53 × 104/ml ± 2.65 × 104/ml, p = 0.045) than those without TCFA.
|
29047360 |
2017 |
|
Rheumatoid Arthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Platelet activation, circulating intermediate monocytes (Mon2) and MPA formation were significantly elevated in RA, especially in those with active disease status.
|
25404518 |
2014 |
|
Autoimmune Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
These findings indicate an important role of platelet activation and the consequent formation of MPA in the generation of the proinflammatory cytokine milieu and for the promotion and maintenance of the pathogenically relevant Mon2 monocyte compartment in RA, which is likely to play an important role in the pathogenesis of autoimmunity.
|
25404518 |
2014 |
|
Leishmaniasis, Visceral
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The escalation in the spread of cutaneous leishmaniasis cases within Sri Lanka and the close resemblance (genotypic and phenotypic) between the local parasite Leishmania donovani MON-37 and the parasite causing visceral leishmaniasis in India (L. donovani MON-2), underscored by the more recent case reports of autochthonous cases of visceral and mucocutaneous-like disease, are clear warnings to the health authorities, scientists and policy makers.
|
19734098 |
2009 |
|
Leishmania donovani disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
Six main genetically distinct populations were identified: (1) L. infantum/L. chagasi MON-1 and (2) L. infantum/L. chagasi non-MON-1, both Mediterranean region/South America; (3) L. donovani (MON-18), L. archibaldi (MON-82), L. infantum (MON-30, 81) and (4) L. donovani (MON-31, 274), L. archibaldi (MON-82, 257, 258), L. infantum (MON-267), both Sudan/Ethiopia; (5) L. donovani MON-2, India; (6) L. donovani (MON-36, 37, 38), Kenya and India.
|
17307010 |
2007 |
|
Leishmania infantum disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
Six main genetically distinct populations were identified: (1) L. infantum/L. chagasi MON-1 and (2) L. infantum/L. chagasi non-MON-1, both Mediterranean region/South America; (3) L. donovani (MON-18), L. archibaldi (MON-82), L. infantum (MON-30, 81) and (4) L. donovani (MON-31, 274), L. archibaldi (MON-82, 257, 258), L. infantum (MON-267), both Sudan/Ethiopia; (5) L. donovani MON-2, India; (6) L. donovani (MON-36, 37, 38), Kenya and India.
|
17307010 |
2007 |
|
Werner Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Expressions in Sf21, as well as in HeLa cells, showed that the WRN DNA helicase is exclusively transported to the nucleoplasm, which is consistent with its function in DNA metabolism.
|
9224595 |
1997 |