Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE miR-361 enhances sensitivity to 5-fluorouracil by targeting the FOXM1-ABCC5/10 signaling pathway in colorectal cancer. 31579069 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE FOXM1 promotes the growth and metastasis of colorectal cancer via activation of β-catenin signaling pathway. 31118796 2019
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE circANKS1B regulates FOXM1 expression and promotes cell migration and invasion by functioning as a sponge of the miR-149 in colorectal cancer. 31213828 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE RhoB plays a critical role in radioresistance of colorectal cancer through Akt and FOXM1 pathways. 31039421 2019
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE FOXM1 modulates 5-FU resistance in colorectal cancer through regulating TYMS expression. 30728402 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE FoxM1 was identified as a down-stream target by mRNA microarray, implying that FoxM1 plays a main role in determining how E2A regulates the tumor-initiating capacity of colorectal cancer. 31234887 2019
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Prognostic and clinicopathological value of FoxM1 expression in colorectal cancer: A systematic review and meta-analysis. 30593202 2018
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Dysregulation of miR-6868-5p/FOXM1 circuit contributes to colorectal cancer angiogenesis. 30486864 2018
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE MicroRNA-761 promotes the sensitivity of colorectal cancer cells to 5-Fluorouracil through targeting FOXM1. 29416616 2018
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Co-inhibition of BET proteins and NF-κB as a potential therapy for colorectal cancer through synergistic inhibiting MYC and FOXM1 expressions. 29472532 2018
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE A novel FOXM1 isoform, FOXM1D, promotes epithelial-mesenchymal transition and metastasis through ROCKs activation in colorectal cancer. 27399334 2017
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Subgroup analysis showed that FOXM1 overexpression was associated with poor prognosis of colorectal cancer, gastric cancer, hepatic cancer, lung cancer and ovarian cancer. 28427178 2017
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE FOXM1 evokes 5-fluorouracil resistance in colorectal cancer depending on ABCC10. 28051999 2017
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE The addition of celecoxib improves the antitumor effect of cetuximab in colorectal cancer: role of EGFR-RAS-FOXM1-β- catenin signaling axis. 28423516 2017
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE FoxM1 is associated with metastasis in colorectal cancer through induction of the epithelial-mesenchymal transition. 29163688 2017
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE In the end, it was determined that Gas1 is a transcriptional target of FOXM1, whose role in colorectal cancer has been widely studied. 27401611 2016
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE MicroRNA-149 Increases the Sensitivity of Colorectal Cancer Cells to 5-Fluorouracil by Targeting Forkhead Box Transcription Factor FOXM1. 27415661 2016
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Overexpression of forkhead box protein M1 (FOXM1) plays a critical role in colorectal cancer. 26370421 2016
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Furthermore, FOXM1 triggered colorectal cancer cell migration and invasion was involved in activities of cell-surface HSPA5. 27034162 2016
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Herein, we performed a systematic and comprehensive discovery step by evaluating the expression of FOX family members, and identified that FOXM1 and FOXQ1 are frequently overexpressed in colorectal cancer. 27162244 2016
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Splenic-injection induced liver metastasis model was used to evaluate the effects of FoxM1-PTTG1 on liver metastasis of colorectal cancer. 26264222 2015
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE FOXM1 expression correlates with tumor invasion and a poor prognosis of colorectal cancer. 22326401 2012
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE These studies suggest that Foxm1 is critical for the proliferation and growth of colorectal cancer. 17408638 2007