FOXO1, forkhead box O1, 2308

N. diseases: 380; N. variants: 16
Disease: Post transplant diabetes mellitus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1504532
Disease: Post transplant diabetes mellitus
Post transplant diabetes mellitus 		0.010 Biomarker disease BEFREE FXR activation may mitigate tacrolimus-induced diabetes mellitus by regulating gluconeogenesis as well as glucose uptake of renal cortex proximal tubule epithelial cells in a PGC1α/FOXO1-dependent manner, which may be a potential therapeutic strategy for the prevention and treatment of PTDM. 31836014 2019