FOXO3, forkhead box O3, 2309

N. diseases: 381; N. variants: 30
Disease: Ovarian Failure, Premature ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085215
Disease: Ovarian Failure, Premature
Ovarian Failure, Premature 		0.030 GeneticVariation disease BEFREE Analysis of FOXO3 mutation in 114 Chinese women with premature ovarian failure. 20219431 2010
CUI: C0085215
Disease: Ovarian Failure, Premature
Ovarian Failure, Premature 		0.030 GeneticVariation disease BEFREE Taken together, our findings suggest that, despite the potential for FOXO3 haploinsufficiency to cause ovarian failure, FOXO3 mutations or common SNPs are not a common cause of either POF or PA. 17959613 2008
CUI: C0085215
Disease: Ovarian Failure, Premature
Ovarian Failure, Premature 		0.030 GeneticVariation disease BEFREE Potentially causal mutations in FOXO3A (2/90; 2.2%) and FOXO1A (1/90; 1.1%) were identified in POF patients; however, the pathological role of these mutations will be determined only by screening increased numbers of patients and controls, or by functional studies. 16979636 2006