FOXO3, forkhead box O3, 2309

N. diseases: 381; N. variants: 30
Disease: Pancreatic carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.050 Biomarker disease BEFREE Taken together, these reaults suggest that the PTEN/FOXO3a/PLZF signalling pathway may be capable of inhibiting growth and metastasis in PC by regulating VEGF-mediated angiogenesis, which requires further in vivo and in vitro studies and can potentially be a therapeutic target for PC. 31087222 2020
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.050 Biomarker disease BEFREE Our study aimed to investigate the interaction between peroxiredoxin 1 (Prx1) and forkhead box O3 (FOXO3) and to explore the role of PI3K/AKT pathway in the development of pancreatic cancer. 30464602 2018
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.050 AlteredExpression disease BEFREE High expression of lncRNA UCA1 and FOXO3 and low expression of miR-96 were shown in pancreatic cancer. 29500870 2018
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.050 AlteredExpression disease BEFREE FOXO3 is essential for CD44 expression in pancreatic cancer cells. 27893718 2017
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.050 GeneticVariation disease BEFREE A functional polymorphism at miR-629-binding site in the 3'-UTR of FOXO3 gene confers a decreased risk of progression in pancreatic carcinoma. 29072689 2017