FLG, filaggrin, 2312

N. diseases: 173; N. variants: 39
Disease: Psoriasis vulgaris ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0263361
Disease: Psoriasis vulgaris
Psoriasis vulgaris 		0.050 Biomarker disease BEFREE The immunostaining pattern of Ki-67, K16, involucrin, and filaggrin may be insufficient to discriminate inflammatory linear verrucous epidermal nevus from psoriasis vulgaris. 29166506 2018
CUI: C0263361
Disease: Psoriasis vulgaris
Psoriasis vulgaris 		0.050 AlteredExpression disease BEFREE Immunohistochemical analysis of skin biopsy samples revealed that the expression levels of filaggrin and MafB were significantly reduced in patients with human atopic dermatitis and psoriasis vulgaris. 27208706 2016
CUI: C0263361
Disease: Psoriasis vulgaris
Psoriasis vulgaris 		0.050 GeneticVariation disease BEFREE Loss-of-function mutations in filaggrin gene associate with psoriasis vulgaris in Chinese population. 22407025 2012
CUI: C0263361
Disease: Psoriasis vulgaris
Psoriasis vulgaris 		0.050 GeneticVariation disease BEFREE A meta-analysis was undertaken to investigate the relation between filaggrin gene mutations and psoriasis vulgaris. 21564328 2012
CUI: C0263361
Disease: Psoriasis vulgaris
Psoriasis vulgaris 		0.050 GeneticVariation disease BEFREE We conclude that despite a markedly altered filaggrin expression in psoriatic skin, loss-of-function variants of the FLG gene are neither associated with psoriasis vulgaris nor with psoriatic arthritis. 17255953 2007