KDM6B, lysine demethylase 6B, 23135

N. diseases: 173; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.020 AlteredExpression disease BEFREE Targeting estrogen receptor beta (ERβ) for treatment of ovarian cancer: importance of KDM6B and SIRT1 for ERβ expression and functionality. 29422491 2018
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.020 Biomarker disease BEFREE Our study demonstrates that co-delivery of PAC and CAR can be achieved with the Fp-PCNs, and reveals a previously unrecognized and unexpected role of the JMJD3-HER2 signaling axis in PAC and CAR treatment of OC. 28849826 2017