USP22, ubiquitin specific peptidase 22, 23326

N. diseases: 65; N. variants: 1
Disease: Malignant neoplasm of colon and/or rectum ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.080 Biomarker disease BEFREE USP22 exerts tumor-suppressive functions in colorectal cancer by decreasing mTOR activity. 31527800 2020
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.080 Biomarker disease BEFREE MiR-30-5p suppresses cell chemoresistance and stemness in colorectal cancer through USP22/Wnt/β-catenin signaling axis. 30338942 2019
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.080 AlteredExpression disease BEFREE USP22-dependent HSP90AB1 expression promotes resistance to HSP90 inhibition in mammary and colorectal cancer. 31801945 2019
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.080 Biomarker disease BEFREE Ubiquitin-Specific Peptidase 22 Contributes to Colorectal Cancer Stemness and Chemoresistance via Wnt/β-Catenin Pathway. 29689565 2018
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.080 Biomarker disease BEFREE USP22 drives colorectal cancer invasion and metastasis via epithelial-mesenchymal transition by activating AP4. 28427243 2017
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.080 Biomarker disease BEFREE Knock-down of ubiquitin-specific protease 22 by micro-RNA interference inhibits colorectal cancer growth. 21773699 2012
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.080 AlteredExpression disease BEFREE Aberrant expression of USP22 is associated with liver metastasis and poor prognosis of colorectal cancer. 21337558 2011
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.080 AlteredExpression disease BEFREE Increased expression of ubiquitin-specific protease 22 can promote cancer progression and predict therapy failure in human colorectal cancer. 21039844 2010