SIRT4, sirtuin 4, 23409

N. diseases: 74; N. variants: 1
Disease: Metabolic Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.030 Biomarker group BEFREE The main goal of this review is to critically analyse and summarise the current research evidence on the significance of the SIRT4 as a metabolic regulator and in mitochondrial function and its putative roles in relation to metabolic diseases and exercise. 31447696 2019
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.030 Biomarker group BEFREE A comprehensive understanding of the enzymology of SIRT4 in metabolism is essential for developing novel therapeutic agents for human metabolic diseases. 30666234 2018
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.030 Biomarker group BEFREE Sirtuin 4 (SIRT4) plays an important role in mitochondrial function and the pathogenesis of metabolic diseases, including aging kidneys. 28123512 2017