SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Disease: Acute pancreatitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.020 AlteredExpression disease BEFREE The serum SIRT1 protein levels were 1495.7 ± 185.9, 2098.3 ± 153.6, 2498.4 ± 198.2, and 3674.3 ± 170.8 pg/ml in the HCs, mild AP, moderately severe AP, and severe AP groups, respectively. 31055719 2019
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.020 AlteredExpression disease BEFREE We demonstrated for the first time that the activities and expression of SIRT1 were suppressed by reduction of intracellular NAD<sup>+</sup> levels and the p53-microRNA-34a pathway in caerulein-induced AP. 28592850 2017